发明授权
- 专利标题: Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
- 专利标题(中): 镧系元素的发光1-羟基-2-吡啶酮螯合物
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申请号: US12373275申请日: 2007-07-10
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公开(公告)号: US08557601B2公开(公告)日: 2013-10-15
- 发明人: Kenneth N. Raymond , Jide Xu , Evan G. Moore , Eric J. Werner
- 申请人: Kenneth N. Raymond , Jide Xu , Evan G. Moore , Eric J. Werner
- 申请人地址: US CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: US CA Oakland
- 代理机构: Morgan, Lewis & Bockius LLP
- 代理商 Jeffrey S. Mann; Todd Esker
- 国际申请: PCT/US2007/073185 WO 20070710
- 国际公布: WO2008/008797 WO 20080117
- 主分类号: G01N33/566
- IPC分类号: G01N33/566 ; G01N21/76 ; C07F5/00 ; C07D213/89
摘要:
The present invention provides luminescent complexes between a lanthanide ion and an organic ligand which contains 1,2-hydroxypyridinone units. The complexes of the invention are stable in aqueous solutions and are useful as molecular probes, for example in medical diagnostics and bioanalytical assay systems. The invention also provides methods of using the complexes of the invention.
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