Invention Grant
US08557848B2 4,5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
有权
用于治疗或预防HCV和相关病毒感染的4,5环环状吲哚衍生物
- Patent Title: 4,5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
- Patent Title (中): 用于治疗或预防HCV和相关病毒感染的4,5环环状吲哚衍生物
-
Application No.: US12519715Application Date: 2007-12-17
-
Publication No.: US08557848B2Publication Date: 2013-10-15
- Inventor: Kevin X. Chen , Srikanth Venkatraman , F. George Njoroge , Stuart B. Rosenblum , Charles A. Lesburg , Jose S. Duca , Neng-Yang Shih , Francisco Velazquez , Gopinadhan N. Anilkumar , Qingbei Zeng , Joseph A. Kozlowski
- Applicant: Kevin X. Chen , Srikanth Venkatraman , F. George Njoroge , Stuart B. Rosenblum , Charles A. Lesburg , Jose S. Duca , Neng-Yang Shih , Francisco Velazquez , Gopinadhan N. Anilkumar , Qingbei Zeng , Joseph A. Kozlowski
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Melissa B. Wenk; Sheldon O. Heber
- International Application: PCT/US2007/025754 WO 20071217
- International Announcement: WO2008/082484 WO 20080710
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/4353 ; A61K31/4439 ; A61K31/444 ; A61K31/4709 ; A61K31/498 ; A61K31/517 ; C07D215/12 ; C07D401/14 ; C07D241/44 ; C07D239/88
Abstract:
The present invention relates to 4,5-ring annulated indole derivatives, compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. Wherein ring Z, of formula (I), is a cyclopentyl, cyclopentenyl, 5-membered heterocycloalkyl, 5-membered heterocycloalkenyl or 5-membered heteroaryl ring.
Public/Granted literature
- US20100098661A1 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS Public/Granted day:2010-04-22
Information query
IPC分类:
