发明授权
- 专利标题： Pyrimidine derivatives used as PI-3 kinase inhibitors
- 专利标题（中）： 用作PI-3激酶抑制剂的嘧啶衍生物
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申请号： US13471111申请日： 2012-05-14
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公开(公告)号： US08563549B2公开(公告)日： 2013-10-22
- 发明人: Matthew Burger , Zhi-Jie Ni , Sabina Pecchi , Gordana Ataliah , Sarah Bartulis , Kelly Frazier , Aaron Smith , Joelle Verhagen , Yanchen Zhang , Allan Wagman , Simon Ng , Keith Pfister , Daniel J. Poon , Alicia Louie , Teresa Pick , Paul Barsanti , Edwin Iwanowicz , Wendy Fantl , Thomas Hendrickson , Mark Knapp , Hanne Meritt , Charles Voliva , Marion Wiesmann , Xiahua Xin
- 申请人： Matthew Burger , Zhi-Jie Ni , Sabina Pecchi , Gordana Ataliah , Sarah Bartulis , Kelly Frazier , Aaron Smith , Joelle Verhagen , Yanchen Zhang , Allan Wagman , Simon Ng , Keith Pfister , Daniel J. Poon , Alicia Louie , Teresa Pick , Paul Barsanti , Edwin Iwanowicz , Wendy Fantl , Thomas Hendrickson , Mark Knapp , Hanne Meritt , Charles Voliva , Marion Wiesmann , Xiahua Xin
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; C07D413/14
摘要：
Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.
公开/授权文献
- US20120225859A1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS 公开/授权日：2012-09-06