A biosafety cabinet device includes one or more walls forming a housing, a work area contained within the housing, a filter in fluid communication with the work area for filtering fluid passing through and exiting the work area. The filter includes a primary filtration surface through which a majority of fluid being filtered by the filter passes. A filter removal device is configured to couple to the filter. The filter removal device includes a rigid barrier layer and one or more handling mechanisms adjoined with the rigid barrier layer and extending distal to the rigid barrier layer. When the filter removal device is securely coupled to the filter, the rigid barrier layer extends substantially across a non-peripheral portion of the primary filtration surface of the filter and allows passage of fluid from the work area through the primary filtration surface of the filter.