发明授权
- 专利标题: C-nitroso-derived nitroxyl donors
- 专利标题(中): C-亚硝基衍生的硝酰基供体
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申请号: US13589422申请日: 2012-08-20
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公开(公告)号: US08569536B2公开(公告)日: 2013-10-29
- 发明人: S. Bruce King
- 申请人: S. Bruce King
- 申请人地址: US NC Winston-Salem
- 专利权人: Wake Forest University Health Sciences
- 当前专利权人: Wake Forest University Health Sciences
- 当前专利权人地址: US NC Winston-Salem
- 代理机构: Myers Bigel Sibley & Sajovec, P.A.
- 主分类号: C07C69/76
- IPC分类号: C07C69/76 ; C07C207/00 ; A61K31/235 ; A61K31/04
摘要:
Active compounds of Formula I are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory drug (NSAID); along with pharmaceutically acceptable salts and prodrug thereof, and methods of using the same.
公开/授权文献
- US20130040919A1 C-NITROSO-DERIVED NITROXYL DONORS 公开/授权日:2013-02-14
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