A radio frequency transmitting system includes a programmable amplifier, a power amplifier, a power detector, and a calibration module. The programmable amplifier is configured to amplify an input signal to generate an amplified signal. The power amplifier is configured to output a transmit signal in response to the amplified signal. The transmit signal has a transmit power. The power detector is configured to generate a power measurement in response to the transmit power. The calibration module is configured to implement a plurality of feedback loops to adjust a gain of the programmable amplifier in response to a difference between the power measurement and a desired transmit power. The calibration module is configured to select one of the plurality of feedback loops in response to the desired transmit power.