发明授权
- 专利标题: Modulation of forkhead box O1A expression
- 专利标题(中): 叉头盒O1A表达式的调制
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申请号: US13531087申请日: 2012-06-22
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公开(公告)号: US08580948B2公开(公告)日: 2013-11-12
- 发明人: Kenneth W. Dobie , Sanjay Bhanot , Robert McKay , Sanjay K. Pandey
- 申请人: Kenneth W. Dobie , Sanjay Bhanot , Robert McKay , Sanjay K. Pandey
- 申请人地址: US CA Carlsbad
- 专利权人: Isis Pharmaceuticals, Inc.
- 当前专利权人: Isis Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Carlsbad
- 代理机构: Knobbe Martens
- 主分类号: C07H21/04
- IPC分类号: C07H21/04
摘要:
Antisense compounds, compositions and methods are provided for modulating the expression of forkhead box O1A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding forkhead box O1A. Methods of using these compounds for modulation of forkhead box O1A expression and for treatment of diseases associated with expression of forkhead box O1A are provided, in particular, for methods of treating diabetes.
公开/授权文献
- US20130030036A1 MODULATION OF FORKHEAD BOX O1A EXPRESSION 公开/授权日:2013-01-31
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