发明授权
- 专利标题： DNA-binding proteins and uses thereof
- 专利标题（中）： DNA结合蛋白及其用途
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申请号： US13068735申请日： 2011-05-17
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公开(公告)号： US08586526B2公开(公告)日： 2013-11-19
- 发明人: Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
- 申请人： Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
- 申请人地址： US CA Richmond
- 专利权人： Sangamo BioSciences, Inc.
- 当前专利权人： Sangamo BioSciences, Inc.
- 当前专利权人地址： US CA Richmond
- 代理机构： Pasternak Patent Law
- 代理商 Danna S. Pasternak
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12Q1/37 ; C12P19/34 ; C07K7/23
摘要：
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
公开/授权文献
- US20110301073A1 Novel DNA-binding proteins and uses thereof 公开/授权日：2011-12-08
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