Invention Grant
US08586576B2 Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
有权
取代的吡唑并[1,5-a]嘧啶作为细胞周期蛋白依赖性激酶抑制剂
- Patent Title: Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
- Patent Title (中): 取代的吡唑并[1,5-a]嘧啶作为细胞周期蛋白依赖性激酶抑制剂
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Application No.: US11710644Application Date: 2007-02-23
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Publication No.: US08586576B2Publication Date: 2013-11-19
- Inventor: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer , Marc Labroli , Kartik M. Keertikar
- Applicant: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer , Marc Labroli , Kartik M. Keertikar
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Joan E. Switzer; David A. Muthard
- Main IPC: A61K31/5513
- IPC: A61K31/5513 ; A61K31/5377 ; A61K31/541 ; A61K31/519 ; A61P35/04 ; A61P35/02 ; A61P35/00 ; C07D487/04 ; C07D295/04 ; C07D243/14
![Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors](/abs-image/US/2013/11/19/US08586576B2/abs.jpg.150x150.jpg)
Abstract:
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Public/Granted literature
- US20070225270A1 Pyrazolopyrimidines as cyclin dependent kinase inhibitors Public/Granted day:2007-09-27
Information query
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