A display substrate includes a switching member, a color filter layer, an inorganic insulation layer and a pixel electrode. The switching member includes a gate line, a data line crossing the gate line, and a thin-film transistor (TFT) electrically connected to the gate line and the data line. The color filter layer is formed on the switching member. The inorganic insulation layer is formed on the color filter layer. The inorganic insulation layer has a hole formed thereon, which exposes a portion of the color filter layer in correspondence with the TFT. The pixel electrode is formed on the inorganic insulation layer.