- 专利标题: Cancer marker, method for evaluation of cancer by using the cancer marker, and evaluation reagent
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申请号: US13472190申请日: 2012-05-15
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公开(公告)号: US08592145B2公开(公告)日: 2013-11-26
- 发明人: Masahiko Kuroda , Masami Tanaka , Kosuke Oikawa , Takayuki Mizutani , Masakatsu Takanashi , Seiko Iizuka , Yoshinori Kosugi , Kazuma Ohyashiki , Akihiko Tsuchida
- 申请人: Masahiko Kuroda , Masami Tanaka , Kosuke Oikawa , Takayuki Mizutani , Masakatsu Takanashi , Seiko Iizuka , Yoshinori Kosugi , Kazuma Ohyashiki , Akihiko Tsuchida
- 申请人地址: JP Tokyo JP Tokyo
- 专利权人: NEC Corporation,Tokyo Medical University
- 当前专利权人: NEC Corporation,Tokyo Medical University
- 当前专利权人地址: JP Tokyo JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2008-119280 20080430
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention provides a novel cancer marker for evaluating the onset, the preclinical stage, the clinical stage, or the prognosis of a cancer in a subject, and an evaluation method using the same. A cancer marker containing at least one miRNA selected from hsa-miR-92 and hsa-miR-494 is used as a marker for cancers excluding breast cancer. A method for evaluating the possibility of cancers excluding breast cancer includes the step of detecting the expression level of a cancer marker in a biological sample collected from a subject. In this method, the cancer marker contains at least one miRNA selected from hsa-miR-92 and hsa-miR-494.
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