The present invention discloses an inter-Node B handover method, wherein a target eNB sends a Handover Request Acknowledge message including handover reference frequency point information through a source eNB to a user equipment, wherein the handover reference frequency point information includes center frequency point information of an uplink component carrier designated for the user equipment to initiate a random access request. Further, the present invention discloses another inter-Node B handover method, wherein a target eNB orderly arrays center frequency point information of uplink component carriers of a target cell to obtain a first list, the target eNB sends a Handover Request Acknowledge message including the first list through a source eNB to a user equipment, and the user equipment requests a random access according to the center frequency point information of a first uplink component carrier. Through the solution of the present invention, the usage rate of the random access resources for the target eNB can be improved effectively and the conflict of random is accesses can be reduced.