A stack of interfolded absorbent sheet products comprises a plurality of absorbent sheets each of which is itself folded at least twice about axes that are perpendicular to one another. Each sheet comprises a first fold that is offset from a line parallel to the first fold bisecting the sheet, and a second fold approximately bisecting the sheet in a direction perpendicular to the first fold. Each sheet is folded such that offset portions of the sheet are positioned interiorly of the sheet when folded. The absorbent sheets preferably have an embossed surface relief of a predetermined pattern or design. Each of the absorbent sheets within the stack comprises at least one pair of panels sandwiched between a pair of adjacent panels of another of the absorbent sheets in the stack.