- 专利标题： Methods and compositions for sleep disorders and other disorders
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申请号： US12994560申请日： 2009-05-27
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公开(公告)号： US08598119B2公开(公告)日： 2013-12-03
- 发明人: Sharon Mates , Allen Fienberg , Lawrence Wennogle
- 申请人： Sharon Mates , Allen Fienberg , Lawrence Wennogle
- 申请人地址： US NY
- 专利权人： Intra-Cellular Therapies, Inc.
- 当前专利权人： Intra-Cellular Therapies, Inc.
- 当前专利权人地址： US NY
- 代理机构： Hoxie & Associates, LLC
- 国际申请： PCT/US2009/003261 WO 20090527
- 国际公布： WO2009/145900 WO 20091203
- 主分类号： A61K38/27
- IPC分类号： A61K38/27 ; A61K31/56 ; A61K31/55 ; A61K31/535 ; A61K31/50 ; A61K31/495 ; A61P5/06 ; A01N45/00 ; A01N43/00 ; A01N43/46 ; A01N43/62 ; A01N43/58 ; A01N43/60
摘要：
Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.
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