Invention Grant
- Patent Title: Compounds for the reduction of beta-amyloid production
- Patent Title (中): 用于减少β-淀粉样蛋白生成的化合物
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Application No.: US13478238Application Date: 2012-05-23
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Publication No.: US08598161B2Publication Date: 2013-12-03
- Inventor: Yong-Jin Wu
- Applicant: Yong-Jin Wu
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent John F. Levis
- Main IPC: C07D513/04
- IPC: C07D513/04 ; C07D279/08

Abstract:
Compounds of formula (I), including pharmaceutically acceptable salts thereof, are set forth herein: wherein R1, R2, R3, R4, R5, and R6 are independently hydrogen, C1-C6 alkyl or C1-C6 cycloalkyl; Y and Z are independently a C6-C10-aryl group or a 5-10 membered heterocyclic group, wherein each Y and Z group can be optionally substituted with from 0-3 substituents selected from halogen, amino, C1-4alkylamino, C1-4dialkylamino, haloC1-4 alkyl, OH, CN, C1-C6 alkyl or cycloalkyl, C1-C6 alkoxy, and C2-C4 alkynyl; L is either a bond or is —NHCO—; L and Z together can be absent; and m is 1, 2 or 3.
Public/Granted literature
- US20130131049A1 COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION Public/Granted day:2013-05-23
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