Invention Grant
US08598172B2 Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
失效
取代的二氢蝶啶-6-酮衍生物，其制备方法及其作为激酶抑制剂的用途
- Patent Title: Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
- Patent Title (中): 取代的二氢蝶啶-6-酮衍生物，其制备方法及其作为激酶抑制剂的用途
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Application No.: US12744770Application Date: 2008-11-26
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Publication No.: US08598172B2Publication Date: 2013-12-03
- Inventor: Michele Caruso , Italo Beria , Maria Gabriella Brasca , Helena Posteri , Gabriele Fachin
- Applicant: Michele Caruso , Italo Beria , Maria Gabriella Brasca , Helena Posteri , Gabriele Fachin
- Applicant Address: IT Nerviano (MI)
- Assignee: Nerviano Medical Sciences S.r.l.
- Current Assignee: Nerviano Medical Sciences S.r.l.
- Current Assignee Address: IT Nerviano (MI)
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP07122297 20071204
- International Application: PCT/EP2008/066253 WO 20081126
- International Announcement: WO2009/071480 WO 20090611
- Main IPC: A61K31/495
- IPC: A61K31/495 ; C07D475/00
Abstract:
Dihydropteridin-6-one derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
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