Invention Grant
US08598177B2 Imidazopyridazines as PAR1 inhibitors, production thereof, and use as medicaments
有权
咪唑并哒嗪作为PAR1抑制剂，其制备及用作药物
- Patent Title: Imidazopyridazines as PAR1 inhibitors, production thereof, and use as medicaments
- Patent Title (中): 咪唑并哒嗪作为PAR1抑制剂，其制备及用作药物
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Application No.: US12851198Application Date: 2010-08-05
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Publication No.: US08598177B2Publication Date: 2013-12-03
- Inventor: Uwe Heinelt , Volkmar Wehner , Matthias Herrmann , Karl Schoenafinger , Henning Steinhagen
- Applicant: Uwe Heinelt , Volkmar Wehner , Matthias Herrmann , Karl Schoenafinger , Henning Steinhagen
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP08290113 20080205
- Main IPC: A61K31/501
- IPC: A61K31/501 ; A61K31/50 ; C07D487/00
Abstract:
The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, Q2 and Q3 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.
Public/Granted literature
- US20110034456A1 IMIDAZOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS Public/Granted day:2011-02-10
Information query
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