Invention Grant
US08598361B2 Process for preparing 5-fluoro-1H-pyrazolo [3,4-B] pyridin-3-amine and derivatives therof
失效
制备5-氟-1H-吡唑并[3,4-B]吡啶-3-胺及其衍生物的方法
![Process for preparing 5-fluoro-1H-pyrazolo [3,4-B] pyridin-3-amine and derivatives therof](/docs/US/2013-12-03/US08598361B2/abs.jpg.600x600.jpg)
- Patent Title: Process for preparing 5-fluoro-1H-pyrazolo [3,4-B] pyridin-3-amine and derivatives therof
- Patent Title (中): 制备5-氟-1H-吡唑并[3,4-B]吡啶-3-胺及其衍生物的方法
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Application No.: US13347926Application Date: 2012-01-11
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Publication No.: US08598361B2Publication Date: 2013-12-03
- Inventor: Juan-Miguel Jimenez , Andrew Miller , Philip Collier , Jeremy Green , Albert Dros , Huai Gao , Sylvain Hamon
- Applicant: Juan-Miguel Jimenez , Andrew Miller , Philip Collier , Jeremy Green , Albert Dros , Huai Gao , Sylvain Hamon
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Rory C. Stewart
- Main IPC: C07D215/04
- IPC: C07D215/04
![Process for preparing 5-fluoro-1H-pyrazolo [3,4-B] pyridin-3-amine and derivatives therof](/abs-image/US/2013/12/03/US08598361B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a process for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine in high yield and purity. The present invention also relates to processes for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine derivatives. These processes are useful for preparing biologically active compounds, particularly certain GSK-3 inhibitors, or derivatives thereof.
Public/Granted literature
- US20120232275A1 PROCESS FOR PREPARING 5-FLUORO-1H-PYRAZOLO [3,4-B] PYRIDIN-3-AMINE AND DERIVATIVES THEREOF Public/Granted day:2012-09-13
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