发明授权
US08604196B2 Modulating signal transduction pathways with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2.3-B]pyrazine-6-yl]thiourea
失效
用1-乙基-3- [3-（1-甲基-1H-吡唑-4-基） - 吡啶并[2,3-B]吡嗪-6-基]硫脲调制信号转导途径
![Modulating signal transduction pathways with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2.3-B]pyrazine-6-yl]thiourea](/docs/US/2013-12-10/US08604196B2/abs.jpg.600x600.jpg)
- 专利标题： Modulating signal transduction pathways with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2.3-B]pyrazine-6-yl]thiourea
- 专利标题（中）： 用1-乙基-3- [3-（1-甲基-1H-吡唑-4-基） - 吡啶并[2,3-B]吡嗪-6-基]硫脲调制信号转导途径
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申请号： US13542101申请日： 2012-07-05
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公开(公告)号： US08604196B2公开(公告)日： 2013-12-10
- 发明人: Matthias Gerlach , Irene Seipelt , Eckhard Guenther , Emmanuel Polymeropoulos , Tilmann Schuster , Eckhard Claus
- 申请人： Matthias Gerlach , Irene Seipelt , Eckhard Guenther , Emmanuel Polymeropoulos , Tilmann Schuster , Eckhard Claus
- 申请人地址： DE Frankfurt am Main
- 专利权人： Aeterna Zentaris GmbH
- 当前专利权人： Aeterna Zentaris GmbH
- 当前专利权人地址： DE Frankfurt am Main
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： EP07107976 20070510
- 主分类号： C07D495/00
- IPC分类号： C07D495/00
![Modulating signal transduction pathways with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2.3-B]pyrazine-6-yl]thiourea](/abs-image/US/2013/12/10/US08604196B2/abs.jpg.150x150.jpg)
摘要：
A method of modulating one or more of ras-Raf-Mek-Erk signal transduction pathway, PI3K-Akt signal transduction pathway and SAPK signal transduction pathway with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2,3-b]pyrazine-6-yl]thiourea, its geometric isomer, or its tautomer.
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