发明授权
US08609104B2 Treatment of B-cell cancers with anti-CD70 antibody-drug conjugates
有权
用抗CD70抗体 - 药物偶联物治疗B细胞癌
- 专利标题： Treatment of B-cell cancers with anti-CD70 antibody-drug conjugates
- 专利标题（中）： 用抗CD70抗体 - 药物偶联物治疗B细胞癌
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申请号： US13491475申请日： 2012-06-07
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公开(公告)号： US08609104B2公开(公告)日： 2013-12-17
- 发明人: Che-leung Law , Alan F. Wahl , Nathalie Scholler , Linda A. Pestano
- 申请人： Che-leung Law , Alan F. Wahl , Nathalie Scholler , Linda A. Pestano
- 申请人地址： US WA Bothell
- 专利权人： Seattle Genetics, Inc.
- 当前专利权人： Seattle Genetics, Inc.
- 当前专利权人地址： US WA Bothell
- 代理机构： Alston & Bird LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of a CD70-expressing cancer, comprising administering to a subject the disclosed pharmaceutical compositions.
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