Invention Grant
US08609676B2 4, 5, 6-trisubstituted pyrimidine derivatives as factor IXa inhibitors
有权
4,5,6,6-三取代嘧啶衍生物作为因子IXa抑制剂
- Patent Title: 4, 5, 6-trisubstituted pyrimidine derivatives as factor IXa inhibitors
- Patent Title (中): 4,5,6,6-三取代嘧啶衍生物作为因子IXa抑制剂
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Application No.: US13388628Application Date: 2010-08-03
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Publication No.: US08609676B2Publication Date: 2013-12-17
- Inventor: Mariappan V. Chelliah , Samuel Chackalamannil , William J. Greenlee , Keith Eagan , Zhuyan Guo , Martin C. Clasby , Yan Xia , Charles L. Jayne , Michael Dwyer , Kartik M. Keertikar , Tin-Yau Chan , Li Wang
- Applicant: Mariappan V. Chelliah , Samuel Chackalamannil , William J. Greenlee , Keith Eagan , Zhuyan Guo , Martin C. Clasby , Yan Xia , Charles L. Jayne , Michael Dwyer , Kartik M. Keertikar , Tin-Yau Chan , Li Wang
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme, Corp.
- Current Assignee: Merck Sharp & Dohme, Corp.
- Current Assignee Address: US NJ Rahway
- Agent Richard S. Parr; Catherine D. Fitch
- International Application: PCT/US2010/044208 WO 20100803
- International Announcement: WO2011/017296 WO 20110210
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505
Abstract:
The present invention relates to novel heterocyclic compounds of Formulae (I): (Chemical formula should be inserted here as it appears on abstract in paper form) Formula (I) as disclosed herein, or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and methods for using said compounds for treating or preventing a thromboembolic disorder.
Public/Granted literature
- US20120136016A1 4, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS Public/Granted day:2012-05-31
Information query
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