发明授权
- 专利标题： Anti-C5a receptor antibodies
- 专利标题（中）： 抗C5a受体抗体
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申请号： US13490093申请日： 2012-06-06
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公开(公告)号： US08613926B2公开(公告)日： 2013-12-24
- 发明人: Kristian Kjaergaard , Soeren Lund , Soeren Berg Padkjaer
- 申请人： Kristian Kjaergaard , Soeren Lund , Soeren Berg Padkjaer
- 申请人地址： DK Bagsvaerd
- 专利权人： Novo Nordisk A/S
- 当前专利权人： Novo Nordisk A/S
- 当前专利权人地址： DK Bagsvaerd
- 代理商 Teresa Chen
- 优先权： EP11168787 20110606; EP12159172 20120313
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/28
摘要：
The present invention concerns human antibodies recognizing the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro-inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.
公开/授权文献
- US20130004514A1 THERAPEUTIC ANTIBODIES 公开/授权日：2013-01-03