Herbicide combinations (A)+(8), if appropriate in the presence of safeners, with an effective content of (A) broad-spectrum herbicides from the group (A1) glufosinate (salts) and related compounds (A2) glyphosate (salts) and related compounds such as sulfosate, (A3) imidazolinones such as imazethapyr, imazapyr, imazaquin, imazamox or their salts and (A4) herbicidal azoles from the group of the protoporphyrinogen oxidase inhibitors (PPO inhibitors) and (A5) the hydroxybenzonitriles and (B) herbicides from the group consisting of (B0) one or more structurally different herbicides from the abovementioned group (A), (B1) foliar- and soil-acting herbicides which are effective against monocotyledonous and dicotyledonous harmful plants, (B2) predominantly foliar-acting herbicides which are effective against dicotyledonous harmful plants, (B3) predominantly foliar-acting herbicides which are effective against monocotyledonous harmful plants, and (B4) foliar- and soil-acting herbicides which are effective against predominantly monocotyledonous harmful plants for controlling harmful plants in tolerant or resistant mutants or transgenic cotton plants.