发明授权
- 专利标题： IRE-1α inhibitors
- 专利标题（中）： IRE-1α抑制剂
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申请号： US12941530申请日： 2010-11-08
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公开(公告)号： US08614253B2公开(公告)日： 2013-12-24
- 发明人: John Bruce Patterson , David Gregory Lonergan , Gary A. Flynn , Qingping Zeng , Peter V. Pallai
- 申请人： John Bruce Patterson , David Gregory Lonergan , Gary A. Flynn , Qingping Zeng , Peter V. Pallai
- 申请人地址： US CA Valencia
- 专利权人： MannKind Corporation
- 当前专利权人： MannKind Corporation
- 当前专利权人地址： US CA Valencia
- 代理机构： Banner & Witcoff, Ltd.
- 主分类号： A61K31/11
- IPC分类号： A61K31/11
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
公开/授权文献
- US20110065162A1 IRE-1alpha INHIBITORS 公开/授权日：2011-03-17
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