发明授权
US08618115B2 Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
有权
取代的噻吩并[3,2-d]嘧啶酮作为MCHR1拮抗剂及其使用方法
![Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them](/docs/US/2013-12-31/US08618115B2/abs.jpg.600x600.jpg)
- 专利标题： Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
- 专利标题（中）： 取代的噻吩并[3,2-d]嘧啶酮作为MCHR1拮抗剂及其使用方法
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申请号： US11586255申请日： 2006-10-25
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公开(公告)号： US08618115B2公开(公告)日： 2013-12-31
- 发明人: William N. Washburn , Mark C. Manfredi , Jeffrey A. Robl , Andres S. Hernandez
- 申请人： William N. Washburn , Mark C. Manfredi , Jeffrey A. Robl , Andres S. Hernandez
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Maureen S. Gibbons; Jing G. Sun
- 主分类号： C07D495/04
- IPC分类号： C07D495/04 ; A61K31/519 ; A61P3/04 ; A61P3/10 ; A61P25/22 ; A61P25/24
![Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them](/abs-image/US/2013/12/31/US08618115B2/abs.jpg.150x150.jpg)
摘要：
The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I.