发明授权
- 专利标题： Therapeutic antibodies
- 专利标题（中）： 治疗性抗体
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申请号： US12316621申请日： 2008-12-15
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公开(公告)号： US08623357B2公开(公告)日： 2014-01-07
- 发明人: Hermann Waldmann , Mark Raymond Frewin , Lisa Kim Gilliland , Luis Richardo Simoes da Silva Graca
- 申请人： Hermann Waldmann , Mark Raymond Frewin , Lisa Kim Gilliland , Luis Richardo Simoes da Silva Graca
- 申请人地址： GB Oxford
- 专利权人： Isis Innovation, Ltd.
- 当前专利权人： Isis Innovation, Ltd.
- 当前专利权人地址： GB Oxford
- 代理商 Elliot M. Olstein; Raymond J. Lillie
- 优先权： GB0024673.6 20001009
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
A pharmaceutical comprising a therapeutic protein that hinds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
公开/授权文献
- US20100015166A1 Therapeutic antibodies 公开/授权日：2010-01-21
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