发明授权
- 专利标题： Blocking mesothelin peptide fragments
- 专利标题（中）： 阻断间皮素肽片段
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申请号： US13133136申请日： 2008-12-05
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公开(公告)号： US08623828B2公开(公告)日： 2014-01-07
- 发明人: Mitchell Ho , Ira Pastan , Osamu Kaneko , Byungkook Lee
- 申请人： Mitchell Ho , Ira Pastan , Osamu Kaneko , Byungkook Lee
- 申请人地址： US DC Washington
- 专利权人： The United States of America as Represented by the Secretary of the Department of Health and Human Services
- 当前专利权人： The United States of America as Represented by the Secretary of the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 国际申请： PCT/US2008/085743 WO 20081205
- 国际公布： WO2010/065044 WO 20100610
- 主分类号： C07K5/00
- IPC分类号： C07K5/00
摘要：
The present invention provides mesothelin peptide fragments corresponding to the CA125 binding site of mesothelin. The peptide fragments find use in disrupting the binding interaction between mesothelin and CA 125, for example, in the treatment and prevention of cancers that require the interaction of mesothelin and CA125 for growth, progression and/or metastasis.
公开/授权文献
- US20110236385A1 BLOCKING MESOTHELIN PEPTIDE FRAGMENTS 公开/授权日：2011-09-29
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