发明授权
- 专利标题: Nucleus pulposus filler
- 专利标题(中): 髓核填充物
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申请号: US13092716申请日: 2011-04-22
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公开(公告)号: US08629122B2公开(公告)日: 2014-01-14
- 发明人: Katsuya Takahashi , Tomoya Sato , Yukihiro Matsuyama
- 申请人: Katsuya Takahashi , Tomoya Sato , Yukihiro Matsuyama
- 申请人地址: JP Tokyo
- 专利权人: Seikagaku Corporation
- 当前专利权人: Seikagaku Corporation
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2004-138034 20040507
- 主分类号: A01N43/04
- IPC分类号: A01N43/04
摘要:
The present invention provides a nucleus pulposus filler or the like which is to be packed into an area in deformed intervertebral disc wherein normal nucleus should be located and can be stabley maintained for a long time More preferably, the present invention provides a nucleus pulposus filler comprising a crosslinked chondroitin sulfate as an active ingredient. The photocrosslinked chondroitin sulfate is preferably the following one: a photocrosslinked chondroitin sulfate obtainable by freezing a photoreactive chondroitin sulfate-containing solution comprising: a photoreactive chondroitin sulfate to which a photoreactive group is bound; an aqueous solvent capable of dissolving the photoreactive chondroitin sulfate; and any one substance selected from the group consisting of an alcohol having aqueous solvent miscibility, a surfactant, and a cheleting agent; irradiating the resulting frozen product with light; and then melting the frozen product. The filler can be provided as a kit by packing it into a container from which the filler can be pushed out.
公开/授权文献
- US20110201570A1 NUCLEUS PULPOSUS FILLER 公开/授权日:2011-08-18