发明授权
- 专利标题： Styrenyl 1,2,4-oxadiazole compounds
- 专利标题（中）： 苯乙烯基-1,2,4-恶二唑化合物
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申请号： US13580928申请日： 2011-02-24
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公开(公告)号： US08629277B2公开(公告)日： 2014-01-14
- 发明人: Meenakshi Sivakumar , Kalpana Sanjay Joshi , Valmik Sopan Aware , Ankush Gangaram Sarde , Sandeep Maruti Bagul , Sonal Mohan Manohar
- 申请人： Meenakshi Sivakumar , Kalpana Sanjay Joshi , Valmik Sopan Aware , Ankush Gangaram Sarde , Sandeep Maruti Bagul , Sonal Mohan Manohar
- 申请人地址： IN Mumbai
- 专利权人： Piramal Enterprises Limited
- 当前专利权人： Piramal Enterprises Limited
- 当前专利权人地址： IN Mumbai
- 代理机构： Ladas & Parry LLP
- 国际申请： PCT/IB2011/050770 WO 20110224
- 国际公布： WO2011/104680 WO 20110901
- 主分类号： C07D413/06
- IPC分类号： C07D413/06 ; C07D271/06
摘要：
The present invention relates to oxadiazole compounds in all their stereoisomeric and tautomeric forms and mixtures thereof in all ratios; and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable prodrugs and pharmaceutically acceptable polymorphs. The invention also relates to processes for the manufacture of the oxadiazole compounds and to pharmaceutical compositions containing them. The said compounds and their pharmaceutical compositions are useful in the treatment of cancer, particularly chronic myeloid leukemia (CML). The present invention further provides a method of treatment of cancer by administering a therapeutically effective amount of said compounds or their pharmaceutical compositions, to a mammal in need thereof.
公开/授权文献
- US20130005771A1 OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE 公开/授权日：2013-01-03
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