The present invention is, in one embodiment, a system and method based on a client-server architecture for seamlessly integrating various information systems. In one embodiment, a bundle of files is deployed to a collaboration client, in order to enable the integration of the collaboration client with disparate information systems and content. In one embodiment, content within a mailbox item is allowed to become a “live” object, and is associated with trigger events, and actions, including sending all or part of the content to a separate information system. In one embodiment, mailbox items are subjected to predefined searches to assess whether they include certain content objects. In another embodiment, panel item elements are visible in the overview panel of the collaboration client. The user may interact with the panel items by dragging content onto them, double clicking them, and invoking actions from a context menu if one is available.