A locking mechanism and an electronic device are provided. The electronic device includes a first body, a second body, a moving module, and a locking mechanism. The moving module is disposed between the first body and the second body, so that the second body is rotatable and tiltable relative to the first body. The locking mechanism includes a first connecting member and a plug. When the plug is coupled with the first connecting member by a magnetic force, the second body is slidable relative to the first body. When the second body is tilted up to decouple the plug from the first connecting member, the plug interferes the moving module, so that the second body is not slidable relative to the first body.