发明授权
US08637244B2 Genetic markers for risk management of atrial fibrillation, atrial flutter, and stroke
有权
用于心房颤动,心房扑动和中风的风险管理的遗传标记
- 专利标题: Genetic markers for risk management of atrial fibrillation, atrial flutter, and stroke
- 专利标题(中): 用于心房颤动,心房扑动和中风的风险管理的遗传标记
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申请号: US12302463申请日: 2007-12-05
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公开(公告)号: US08637244B2公开(公告)日: 2014-01-28
- 发明人: Anna Helgadottir , Daniel Gudbjartsson
- 申请人: Anna Helgadottir , Daniel Gudbjartsson
- 申请人地址: IS Reykjavik
- 专利权人: deCODE Genetics ehf.
- 当前专利权人: deCODE Genetics ehf.
- 当前专利权人地址: IS Reykjavik
- 代理机构: Marshall, Gerstein & Borun LLP
- 优先权: IS8576 20061205; IS8658 20070629
- 国际申请: PCT/IS2007/000021 WO 20071205
- 国际公布: WO2008/068780 WO 20080612
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/48 ; A61B5/02 ; C07H21/04
摘要:
The invention relates to procedure and methods of determining a susceptibility to cardiac arrhythmia, including Atrial Fibrillation, Atrial Flutter and Stroke, by assessing the presence or absence of alleles at polymorphic markers found to be associated with Atrial Fibrillation, Atrial Flutter and Stroke. The invention further relates to kits encompassing reagents for assessing such markers, and diagnostic methods, uses and procedures for utilizing such susceptibility markers.
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