Invention Grant
US08637670B2 Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation
失效
咪唑并[4,5-C]喹啉衍生物及其在治疗肿瘤和/或炎症中的应用
![Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation](/docs/US/2014-01-28/US08637670B2/abs.jpg.600x600.jpg)
- Patent Title: Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation
- Patent Title (中): 咪唑并[4,5-C]喹啉衍生物及其在治疗肿瘤和/或炎症中的应用
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Application No.: US13381464Application Date: 2009-06-30
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Publication No.: US08637670B2Publication Date: 2014-01-28
- Inventor: Sanjay Kumar , Ram Vishwakarma , Ramswaroop Mundada , Vijaykumar Deore , Pramod Kumar , Somesh Sharma
- Applicant: Sanjay Kumar , Ram Vishwakarma , Ramswaroop Mundada , Vijaykumar Deore , Pramod Kumar , Somesh Sharma
- Applicant Address: IN Mumbai
- Assignee: Piramal Enterprises Limited
- Current Assignee: Piramal Enterprises Limited
- Current Assignee Address: IN Mumbai
- Agency: Ladas & Parry LLP
- International Application: PCT/IB2009/052819 WO 20090630
- International Announcement: WO2011/001212 WO 20110106
- Main IPC: C07D471/12
- IPC: C07D471/12 ; A61K31/122
![Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation](/abs-image/US/2014/01/28/US08637670B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides the compounds of formula (I): The present invention relates to imidazo[4,5-c]quinoline derivatives of formula (I), process for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by phosphatidylinositol-3-kinase (PBK) and/or mammalian target of rapamycin (mTOR) and/or tumor necrosis factor-α (TNF-oc) and/or interleukin-6 (IL-6), particularly in the treatment of cancer and inflammation.
Public/Granted literature
- US20120108627A1 IMIDAZO [4,5-C]QUINOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF TUMORS AND/OR INFLAMMATION Public/Granted day:2012-05-03
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