发明授权
US08642548B2 Val (8) GLP-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome
有权
Val（8）GLP-1组合物和治疗功能性消化不良和/或肠易激综合征的方法
- 专利标题： Val (8) GLP-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome
- 专利标题（中）： Val（8）GLP-1组合物和治疗功能性消化不良和/或肠易激综合征的方法
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申请号： US13389410申请日： 2010-08-05
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公开(公告)号： US08642548B2公开(公告)日： 2014-02-04
- 发明人: Peter Richardson , Enda Kenny , Per Hellstrom , Marshall L. Grant , Grayson W. Stowell , Scott Daniels , Anthony Smithson , Stephanie Greene
- 申请人： Peter Richardson , Enda Kenny , Per Hellstrom , Marshall L. Grant , Grayson W. Stowell , Scott Daniels , Anthony Smithson , Stephanie Greene
- 申请人地址： US CA Valencia
- 专利权人： Mannkind Corporation
- 当前专利权人： Mannkind Corporation
- 当前专利权人地址： US CA Valencia
- 代理机构： K&L Gates LLP
- 代理商 Louis C. Cullman; Hal Gibson
- 国际申请： PCT/US2010/044600 WO 20100805
- 国际公布： WO2011/017554 WO 20110210
- 主分类号： A61K38/26
- IPC分类号： A61K38/26 ; A61P3/10 ; A61P7/12 ; C07K14/605
摘要：
A method of treating functional dyspepsia and/or irritable bowel syndrome in mammals in need of treatment is disclosed herein. The method comprises administering to the mammal a formulation by inhalation, wherein the formulation avoids first pass metabolism of the active ingredient. The method comprises administering a formulation by pulmonary inhalation comprising a diketopiperazine and a glucagon-like peptide (GLP-1), analog, ROSE-010.
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