发明授权
- 专利标题: Central nervous system labelling composition for intranasal administration and labelling method and screening method using central nervous system labelling composition for intranasal administration
- 专利标题(中): 用于鼻内给药的中枢神经系统标记组合物和用于鼻内给药的中枢神经系统标记组合物的标记方法和筛选方法
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申请号: US13084971申请日: 2011-04-12
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公开(公告)号: US08652438B2公开(公告)日: 2014-02-18
- 发明人: Tsuyoshi Nomoto , Kohei Watanabe , Taichi Shintou , Takeshi Miyazaki , Toshio Tanaka , Yuhei Nishimura , Yasuhito Shimada
- 申请人: Tsuyoshi Nomoto , Kohei Watanabe , Taichi Shintou , Takeshi Miyazaki , Toshio Tanaka , Yuhei Nishimura , Yasuhito Shimada
- 申请人地址: JP Tokyo
- 专利权人: Canon Kabushiki Kaisha
- 当前专利权人: Canon Kabushiki Kaisha
- 当前专利权人地址: JP Tokyo
- 代理机构: Fitzpatrick, Cella, Harper & Scinto
- 优先权: JP2009-296329 20091225
- 主分类号: A61K51/00
- IPC分类号: A61K51/00 ; A61M36/14
摘要:
There is provided a central nervous system labelling composition for intranasal administration for the purpose of labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration. Additionally, there is provided a method of non-invasively labelling the central nervous system by way of an administration route that entails little transferability to the entire body. Furthermore, there is provided a screening method using a central nervous system labelling composition for intranasal administration. A central nervous system labelling composition for intranasal administration is characterized by labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration and by containing at least one compound expressed either by the general formula (1) or the general formula (2) shown below as effective component:
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