Invention Grant
- Patent Title: Analysis of ex vivo cells for disease state detection and therapeutic agent selection and monitoring
- Patent Title (中): 疾病状态检测和治疗剂选择和监测的离体细胞分析
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Application No.: US12993826Application Date: 2008-12-01
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Publication No.: US08652798B2Publication Date: 2014-02-18
- Inventor: James K. Gimzewski , Sarah E. Cross , Yusheng Jin , Jianyu Rao
- Applicant: James K. Gimzewski , Sarah E. Cross , Yusheng Jin , Jianyu Rao
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Foley & Lardner LLP
- Agent Cliff Z. Liu
- International Application: PCT/US2008/085194 WO 20081201
- International Announcement: WO2009/142661 WO 20091126
- Main IPC: C12Q1/02
- IPC: C12Q1/02 ; B82B3/00
Abstract:
Described herein is the analysis of nanomechanical characteristics of cells. In particular, changes in certain local nanomechanical characteristics of ex vivo human cells can correlate with presence of a human disease, such as cancer, as well as a particular stage of progression of the disease. Also, for human patients that are administered with a therapeutic agent, changes in local nanomechanical characteristics of ex vivo cells collected from the patients can correlate with effectiveness of the therapeutic agent in terms of impeding or reversing progression of the disease. By exploiting this correlation, systems and related methods can be advantageously implemented for disease state detection and therapeutic agent selection and monitoring.
Public/Granted literature
- US20110070604A1 ANALYSIS OF EX VIVO CELLS FOR DISEASE STATE DETECTION AND THERAPEUTIC AGENT SELECTION AND MONITORING Public/Granted day:2011-03-24
Information query
