发明授权
US08653069B2 Aralkyl substituted piperidine or piperazine derivatives and their use for treating schizophrenia
有权
芳烷基取代的哌啶或哌嗪衍生物及其用于治疗精神分裂症的用途
- 专利标题： Aralkyl substituted piperidine or piperazine derivatives and their use for treating schizophrenia
- 专利标题（中）： 芳烷基取代的哌啶或哌嗪衍生物及其用于治疗精神分裂症的用途
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申请号： US13056365申请日： 2008-07-28
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公开(公告)号： US08653069B2公开(公告)日： 2014-02-18
- 发明人: Jianqi Li , Shaoping Peng , Wangping Cai , Kai Gao
- 申请人： Jianqi Li , Shaoping Peng , Wangping Cai , Kai Gao
- 申请人地址： CN Nanjing, Jiangsu Province
- 专利权人： Jiangsu Hengyi Pharmaceutical Co., Ltd.
- 当前专利权人： Jiangsu Hengyi Pharmaceutical Co., Ltd.
- 当前专利权人地址： CN Nanjing, Jiangsu Province
- 代理机构： Andrus Intellectual Property Law, LLP
- 国际申请： PCT/CN2008/001385 WO 20080728
- 国际公布： WO2010/012121 WO 20100204
- 主分类号： A61K31/536
- IPC分类号： A61K31/536 ; A61K31/496 ; A61K31/4545 ; C07D413/12 ; C07D413/14
摘要：
The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula.
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