发明授权
- 专利标题： Calcium salts of compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
- 专利标题（中）： 化合物的钙盐作为抗炎，免疫调节和抗增殖剂
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申请号： US13174899申请日： 2011-07-01
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公开(公告)号： US08653138B2公开(公告)日： 2014-02-18
- 发明人: Aldo Ammendola , Julia Diederichs , Johann Leban , Daniel Vitt
- 申请人： Aldo Ammendola , Julia Diederichs , Johann Leban , Daniel Vitt
- 申请人地址： DE Planegg-Martinsried
- 专利权人： 4SC MG
- 当前专利权人： 4SC MG
- 当前专利权人地址： DE Planegg-Martinsried
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 主分类号： A61K31/195
- IPC分类号： A61K31/195 ; A61K31/19 ; C07C229/00
摘要：
The present invention relates to calcium salts of compounds of the general formula (I) wherein X is selected from the group consisting of CH2, S, or O; D is O or S; R8 is hydrogen or alkyl; E is an optionally substituted phenylene group; Y is a monocyclic or bicyclic substituted or unsubstituted 6-9 membered ring system which may contain one or more heteroatoms selected from N or S and which contains at least one aromatic ring; n is 0 or 1, and q is 0 or 1; with the proviso that compounds wherein X═CH2, q=0, Y=unsubstituted phenyl and E=unsubstituted phenylene are excluded; or a hydrate thereof.
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