发明授权
- 专利标题： Derivatives of pyridoxine for inhibiting HIV integrase
- 专利标题（中）： 吡哆醇用于抑制HIV整合酶的衍生物
-
申请号： US13605502申请日： 2012-09-06
-
公开(公告)号： US08664248B2公开(公告)日： 2014-03-04
- 发明人: Brent Richard Stranix , Guy Milot , Jean-Emmanuel Bouchard
- 申请人： Brent Richard Stranix , Guy Milot , Jean-Emmanuel Bouchard
- 申请人地址： TW Taipei
- 专利权人： TaiMed Biologics, Inc.
- 当前专利权人： TaiMed Biologics, Inc.
- 当前专利权人地址： TW Taipei
- 代理机构： Clark & Elbing LLP
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D213/62 ; C07D213/78
摘要：
The present invention relates to methods of treating hepatitis C infection, HIV infection, AIDS, or AIDS-related complex, or inhibiting HIV replication by administering a compound of Formula I wherein: X is H or OH; Y is H or OH; R1 is H or halogen (F, Cl, Br, I); R2 is H or halogen (F, Cl, Br, I); R3 is H, C1-6 alkyl, C1-6 fluoroalkyl, or benzyl; R4 is H, C1-6 alkyl, or benzyl; and R5 is H or C1-6 alkyl; or pharmaceutically acceptable salts thereof, to a mammal.
公开/授权文献
- US20120329827A1 DERIVATIVES OF PYRIDOXINE FOR INHIBITING HIV INTEGRASE 公开/授权日：2012-12-27