A method programming a non-volatile memory device using an incremental step pulse programming (ISPP) scheme is disclosed. The method includes operating in a first program mode during which a program pulse width is constant and a program voltage is successively increased per ISPP cycle, and during which a program operation and a verify operation are alternately repeated, and operating in a second program mode during which the program pulse width is successively increased per ISPP cycle and the program voltage is constant, and during which the program operation and the verify operation are alternately repeated, wherein operation in the second program mode follows operation in the first program mode only when the program voltage equals a maximum value, or when a verification result count value satisfies a predetermined condition.