Communication processing paths include distortions, such as DC offset in the baseband analog path, local oscillator feed-through distortion, and nonlinearity of gm's and power amplifiers which are calibrated for, separately or in combination. The cascaded DC offset and nonlinear distortions are modeled separately or in combination using even-and-odd order polynomials. A loopback path from the output of one or more distortion causing devices passes through a measurement and calculation module. The calculation module calculates predistortion polynomial's coefficients which will be stored in a look-up table to be used by a baseband predistorter to calibrate the path. The look-up table is stored locally or remotely.