Invention Grant
- Patent Title: Poly (ADP-ribose) polymerase (PARP) inhibitors
- Patent Title (中): 聚（ADP-核糖）聚合酶（PARP）抑制剂
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Application No.: US13260680Application Date: 2010-03-26
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Publication No.: US08669249B2Publication Date: 2014-03-11
- Inventor: Jason W. Brown , Anthony R. Gangloff , Andrew John Jennings , Phong H. Vu
- Applicant: Jason W. Brown , Anthony R. Gangloff , Andrew John Jennings , Phong H. Vu
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo; Mitchell R. Brustein
- International Application: PCT/US2010/028878 WO 20100326
- International Announcement: WO2010/111626 WO 20100930
- Main IPC: C07D265/36
- IPC: C07D265/36 ; C07D413/06 ; A61K31/538
Abstract:
Compounds of the following formula are provided for use in inhibiting Poly (ADP-ribose) Polymerase (PARP): wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds.
Public/Granted literature
- US20120094992A1 POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS Public/Granted day:2012-04-19
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