- 专利标题： 2,5-disubstituted piperidine orexin receptor antagonists
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申请号： US13124897申请日： 2009-10-15
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公开(公告)号： US08669272B2公开(公告)日： 2014-03-11
- 发明人: Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , John D. Schreier , David B. Whitman
- 申请人： Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , John D. Schreier , David B. Whitman
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 J. Eric Thies; John C. Todaro
- 国际申请： PCT/US2009/060736 WO 20091015
- 国际公布： WO2010/048010 WO 20100429
- 主分类号： A61K31/4725
- IPC分类号： A61K31/4725 ; A61K31/472 ; A61K31/454 ; C07D401/14
摘要：
The present invention is directed to 2,5-disubstituted piperidine amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
公开/授权文献
- US20110251237A1 2,5-Disubstituted Piperidine Orexin Receptor Antagonists 公开/授权日：2011-10-13
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