Invention Grant
US08673890B2 2,3-dihydro-1H-isoindol-1-imine derivatives useful as thrombin PAR-1 receptor antagonist
失效
可用作凝血酶PAR-1受体拮抗剂的2,3-二氢-1H-异吲哚-1-亚胺衍生物
- Patent Title: 2,3-dihydro-1H-isoindol-1-imine derivatives useful as thrombin PAR-1 receptor antagonist
- Patent Title (中): 可用作凝血酶PAR-1受体拮抗剂的2,3-二氢-1H-异吲哚-1-亚胺衍生物
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Application No.: US12913989Application Date: 2010-10-28
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Publication No.: US08673890B2Publication Date: 2014-03-18
- Inventor: Han-Cheng Zhang , Bruce Maryanoff , Kimberly White , Stephen C. Yabut , Hong Ye , Cailin Chen
- Applicant: Han-Cheng Zhang , Bruce Maryanoff , Kimberly White , Stephen C. Yabut , Hong Ye , Cailin Chen
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Agent Yuriy P. Stercho
- Main IPC: A61K31/33
- IPC: A61K31/33 ; A61K31/335 ; C07D491/02 ; C07D321/10

Abstract:
The present invention is directed to novel 2,3-dihydro-1H-isoindol-1-imine derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the thrombin PAR-1 receptor antagonists.
Public/Granted literature
- US20110105490A1 2,3-DIHYDRO-1H-ISOINDOL-1-IMINE DERIVATIVES USEFUL AS THROMBIN PAR-1 RECEPTOR ANTAGONIST Public/Granted day:2011-05-05
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