发明授权
- 专利标题: Oxazole derivatives useful as inhibitors of FAAH
- 专利标题(中): 恶唑衍生物可用作FAAH的抑制剂
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申请号: US13057415申请日: 2009-07-30
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公开(公告)号: US08673941B2公开(公告)日: 2014-03-18
- 发明人: Harry Chobanian , Linus S. Lin , Ping Liu , Marc D. Chioda , Robert J. DeVita , Ravi P. Nargund , Yan Guo
- 申请人: Harry Chobanian , Linus S. Lin , Ping Liu , Marc D. Chioda , Robert J. DeVita , Ravi P. Nargund , Yan Guo
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Maria V. Marucci
- 国际申请: PCT/US2009/052171 WO 20090730
- 国际公布: WO2010/017079 WO 20100211
- 主分类号: A01N43/40
- IPC分类号: A01N43/40 ; A61K31/44
摘要:
The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.
公开/授权文献
- US20110144119A1 OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH 公开/授权日:2011-06-16
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