Invention Grant
- Patent Title: Oxazole derivatives useful as inhibitors of FAAH
- Patent Title (中): 恶唑衍生物可用作FAAH的抑制剂
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Application No.: US13057415Application Date: 2009-07-30
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Publication No.: US08673941B2Publication Date: 2014-03-18
- Inventor: Harry Chobanian , Linus S. Lin , Ping Liu , Marc D. Chioda , Robert J. DeVita , Ravi P. Nargund , Yan Guo
- Applicant: Harry Chobanian , Linus S. Lin , Ping Liu , Marc D. Chioda , Robert J. DeVita , Ravi P. Nargund , Yan Guo
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Maria V. Marucci
- International Application: PCT/US2009/052171 WO 20090730
- International Announcement: WO2010/017079 WO 20100211
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44
Abstract:
The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.
Public/Granted literature
- US20110144119A1 OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH Public/Granted day:2011-06-16
Information query
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