Invention Grant
- Patent Title: Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
- Patent Title (中): 用精氨酸剥夺治疗人类恶性肿瘤的药物制剂及方法
-
Application No.: US11673601Application Date: 2007-02-12
-
Publication No.: US08679810B2Publication Date: 2014-03-25
- Inventor: Ning Man Cheng , Yun Chung Leung , Wai Hung Lo
- Applicant: Ning Man Cheng , Yun Chung Leung , Wai Hung Lo
- Applicant Address: CN Hong Kong
- Assignee: Bio-Cancer Treatment International Limited
- Current Assignee: Bio-Cancer Treatment International Limited
- Current Assignee Address: CN Hong Kong
- Agency: Eagle IP Limited
- Agent Jacqueline C. Lui
- Priority: WOPCT/CN02/00635 20020909
- Main IPC: C12N9/96
- IPC: C12N9/96 ; C12N9/14 ; C12N9/78 ; C12P21/06 ; A61K38/46 ; A61K38/00 ; C07H21/04
Abstract:
The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.
Public/Granted literature
- US20080248018A1 PHARMACEUTICAL PREPARATION AND METHOD OF TREATMENT OF HUMAN MALIGNANCIES WITH ARGININE DEPRIVATION Public/Granted day:2008-10-09
Information query
