Invention Grant
- Patent Title: Spiro-oxindole MDM2 antagonists
- Patent Title (中): 螺羟吲哚MDM2拮抗剂
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Application No.: US13294315Application Date: 2011-11-11
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Publication No.: US08680132B2Publication Date: 2014-03-25
- Inventor: Shaomeng Wang , Wei Sun
- Applicant: Shaomeng Wang , Wei Sun
- Applicant Address: US MI Ann Arbor US DE Wilmington FR Paris
- Assignee: The Regents of the University of Michigan,Ascenta Licensing Corporation,Sanofi
- Current Assignee: The Regents of the University of Michigan,Ascenta Licensing Corporation,Sanofi
- Current Assignee Address: US MI Ann Arbor US DE Wilmington FR Paris
- Agency: Casimir Jones SC
- Main IPC: A61K31/4015
- IPC: A61K31/4015 ; C07D209/34
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
Public/Granted literature
- US20120122947A1 SPIRO-OXINDOLE MDM2 ANTAGONISTS Public/Granted day:2012-05-17
Information query
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