发明授权
- 专利标题: Orally active curcuminoid compounds
- 专利标题(中): 口服活性姜黄素化合物
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申请号: US13002588申请日: 2009-07-06
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公开(公告)号: US08680143B2公开(公告)日: 2014-03-25
- 发明人: Ramchand Nanappan Chaniyilparampu , Anitha Krishnan Nair , Anuj Kapoor , Kiran Bhupathiraju , Rama Raju Gokaraju , Ganga Raju Gokaraju , Trimurtulu Golakoti , Venkateswarlu Somepalli
- 申请人: Ramchand Nanappan Chaniyilparampu , Anitha Krishnan Nair , Anuj Kapoor , Kiran Bhupathiraju , Rama Raju Gokaraju , Ganga Raju Gokaraju , Trimurtulu Golakoti , Venkateswarlu Somepalli
- 申请人地址: US IN Chennai
- 专利权人: Laila Pharmaceuticals Pvt. Ltd.
- 当前专利权人: Laila Pharmaceuticals Pvt. Ltd.
- 当前专利权人地址: US IN Chennai
- 代理机构: Kramer Amado, P.C.
- 优先权: IN1641/CHE/2008 20080707
- 国际申请: PCT/IN2009/000382 WO 20090706
- 国际公布: WO2010/004579 WO 20100114
- 主分类号: A01N37/02
- IPC分类号: A01N37/02 ; A01N37/06 ; A61K31/225
摘要:
The invention discloses a compound of formula (I) wherein, at least one of R1, R2, R3 and R4 is —C(═O)Rn and R1, R2R3 and R4 are H or CH3 and Rn is alkyl or alkenyl group. The alkenyl group have one or more number of double bonds either in cis form or trans form or both. In Rn, where n is 12 to 30 carbons; and pharmaceutically acceptable salt thereof. The said alkenyl groups are preferably selected from the group consisting of eicosapentaenoic acid (EPA) or DHA (docosahexaenoic acid). This invention further discloses processes for their preparation of compounds of formula I and pharmaceutical compositions that contain these compounds.
公开/授权文献
- US20110112190A1 ORALLY ACTIVE CURCUMINOID COMPOUNDS 公开/授权日:2011-05-12
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