Disclosed herein is a TPMS transmission module having a power saving function, the TPMS transmission module including: a micom outputting a switch turn-off control signal when a vehicle having the TPMS transmission module mounted therein is stopped; a switch supplying a power when the switch is turned on and blocking the supply of the power when it is turned off; an energy generator generating and outputting an electric power when a tire rotates; and a switch controller turning on the switch when the electric power of a predetermined voltage or more is generated in the energy generator and turning off the switch when a switch turn off control signal is output from the micom.